Enables guanyl-nucleotide exchange factor activity. Involved in small GTPase-mediated signal transduction. Located in cytoplasm. Orthologous to human NET1 (neuroepithelial cell transforming 1).
SGD Description
Guanine nucleotide exchange factor (GEF) for Rho1p; mutations are synthetically lethal with mutations in rom2, which also encodes a GEP; ROM1 has a paralog, ROM2, that arose from the whole genome duplication