Gene

ROM1

Species
Saccharomyces cerevisiae
Symbol
ROM1
Name
RhO1 Multicopy suppressor
Synonyms
  • SKC1
  • YGR070W
Biotype
protein coding gene
Automated Description
Enables guanyl-nucleotide exchange factor activity. Involved in small GTPase-mediated signal transduction. Located in cytoplasm. Orthologous to human NET1 (neuroepithelial cell transforming 1).
SGD Description
Guanine nucleotide exchange factor (GEF) for Rho1p; mutations are synthetically lethal with mutations in rom2, which also encodes a GEP; ROM1 has a paralog, ROM2, that arose from the whole genome duplication
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46572:SF2
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
628.0k628.5k629.0k629.5k630.0k630.5k631.0k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions