Gene

MSM1

Species
Saccharomyces cerevisiae
Symbol
MSM1
Name
Mitochondrial aminoacyl-tRNA Synthetase, Methionine
Synonyms
  • YGR171C
Biotype
protein coding gene
Automated Description
Enables methionine-tRNA ligase activity. Involved in methionyl-tRNA aminoacylation. Located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 25 and spastic ataxia 3. Orthologous to human MARS2 (methionyl-tRNA synthetase 2, mitochondrial).
SGD Description
Mitochondrial methionyl-tRNA synthetase (MetRS); functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43326:SF1
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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841.0k841.2k841.4k841.6k841.8k842.0k842.2k842.4k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions