Gene

PFK1

Species
Saccharomyces cerevisiae
Symbol
PFK1
Name
PhosphoFructoKinase
Synonyms
  • YGR240C
Biotype
protein coding gene
Automated Description
Contributes to 6-phosphofructokinase activity. Involved in glycolytic process and regulation of intracellular pH. Located in mitochondrion. Part of 6-phosphofructokinase complex. Used to study glycogen storage disease. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Orthologous to human PFKL (phosphofructokinase, liver type); PFKM (phosphofructokinase, muscle); and PFKP (phosphofructokinase, platelet).
SGD Description
Alpha subunit of heterooctameric phosphofructokinase; involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13697:SF57
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
971.0k971.5k972.0k972.5k973.0k973.5k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions