Gene

ELO1

Species
Saccharomyces cerevisiae
Symbol
ELO1
Name
ELOngation defective
Synonyms
  • YJL196C
Biotype
protein coding gene
Automated Description
Enables fatty acid elongase activity. Involved in fatty acid elongation, unsaturated fatty acid. Located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 38. Orthologous to several human genes including ELOVL3 (ELOVL fatty acid elongase 3) and ELOVL6 (ELOVL fatty acid elongase 6).
SGD Description
Elongase I, medium-chain acyl elongase; catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids; ELO1 has a paralog, ELO2, that arose from the whole genome duplication
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11157:SF159
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
67.9k68.0k68.1k68.2k68.3k68.4k68.5k68.6k68.7k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions