Enables fatty acid elongase activity. Involved in fatty acid elongation, unsaturated fatty acid. Located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 38. Orthologous to several human genes including ELOVL3 (ELOVL fatty acid elongase 3) and ELOVL6 (ELOVL fatty acid elongase 6).
SGD Description
Elongase I, medium-chain acyl elongase; catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids; ELO1 has a paralog, ELO2, that arose from the whole genome duplication