Gene

BAT2

Species
Saccharomyces cerevisiae
Symbol
BAT2
Name
Branched-chain Amino acid Transaminase
Synonyms
  • ECA40
  • TWT2
Biotype
protein coding gene
Automated Description
Enables branched-chain-amino-acid transaminase activity. Involved in branched-chain amino acid biosynthetic process and branched-chain amino acid catabolic process. Located in cytoplasm. Human ortholog(s) of this gene implicated in hypervalinemia and hyperleucine-isoleucinemia. Orthologous to several human genes including BCAT2 (branched chain amino acid transaminase 2).
SGD Description
Cytosolic branched-chain amino acid (BCAA) aminotransferase; preferentially involved in BCAA catabolism; homolog of murine ECA39; highly expressed during stationary phase and repressed during logarithmic phase; BAT2 has a paralog, BAT1, that arose from the whole genome duplication
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11825:SF44
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
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    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
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        Models

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        Associated Human Diseases
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          Sequence Feature Viewer

          Genome location
          Assembly version
          R64-5-1
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          BAT2 molecule type
          Interactor gene
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          Interactor molecule type
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            Genetic Interactions

            BAT2 role
            BAT2 genetic perturbation
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