Version: 8.0.0
Date: Tue Jan 28 2025
SNF7
Saccharomyces cerevisiaeSGD:S000004015
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

SNF7

Species
Saccharomyces cerevisiae
Symbol
SNF7
Name
Sucrose NonFermenting
Synonyms
  • DID1
  • RNS4
Biotype
protein coding gene
Automated Description
Involved in several processes, including ATP export; ESCRT III complex assembly; and intralumenal vesicle formation. Located in cytoplasm and plasma membrane. Part of ESCRT III complex. Human ortholog(s) of this gene implicated in cataract 31 multiple types. Orthologous to several human genes including CHMP4A (charged multivesicular body protein 4A); CHMP4B (charged multivesicular body protein 4B); and CHMP4C (charged multivesicular body protein 4C).
SGD Description
One of four core subunits of the ESCRT-III complex; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes; subunit of the endosomal sorting complex required for transport III (ESCRT-III) that forms flat spirals on lipid monolayers as part of the complexes role in driving membrane abscission
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22761:SF10
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          R64-5-1
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          SNF7 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            SNF7 role
            SNF7 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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