Gene

STM1

Species
Saccharomyces cerevisiae
Symbol
STM1
Name
Suppressor of ToM1
Synonyms
  • MPT4
  • YLR150W
Biotype
protein coding gene
Automated Description
Enables ribosome binding activity; telomeric DNA binding activity; and triplex DNA binding activity. Involved in several processes, including TOR signaling; regulation of translational initiation in response to stress; and telomere maintenance. Located in cytoplasm.
SGD Description
Ribosome preservation factor; required for optimal translation under nutrient stress; forms dormant 80S ribosomes upon TORC1 inhibition, protects ribosomes from proteasomal degradation; perturbs association of Yef3p with ribosomes; binds G4 quadruplex and purine motif triplex nucleic acid; helps maintain telomere structure; protein abundance increases in response to DNA replication stress
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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440.5k440.6k440.7k440.8k440.9k441.0k441.1k441.2k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions