Gene

MAS1

Species
Saccharomyces cerevisiae
Symbol
MAS1
Name
Mitochondrial ASsembly
Synonyms
  • MIF1
  • YLR163C
Biotype
protein coding gene
Automated Description
Contributes to metalloendopeptidase activity. Involved in protein processing involved in protein targeting to mitochondrion. Located in mitochondrion. Part of mitochondrial processing peptidase complex. Used to study multiple mitochondrial dysfunctions syndrome 6. Human ortholog(s) of this gene implicated in Alzheimer's disease and multiple mitochondrial dysfunctions syndrome 6. Orthologous to several human genes including PMPCB (peptidase, mitochondrial processing subunit beta).
SGD Description
Beta subunit of the mitochondrial processing protease (MPP); essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11851:SF149
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
492.0k492.2k492.4k492.6k492.8k493.0k493.2k

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions