Gene

APS1

Species
Saccharomyces cerevisiae
Symbol
APS1
Name
clathrin Associated Protein complex Small subunit
Synonyms
  • YAP19
  • YLR170C
Biotype
protein coding gene
Automated Description
Predicted to enable clathrin adaptor activity. Involved in Golgi to vacuole transport. Part of AP-1 adaptor complex. Human ortholog(s) of this gene implicated in MEDNIK syndrome; psoriasis 15; and syndromic X-linked intellectual disability 5. Orthologous to several human genes including AP1S1 (adaptor related protein complex 1 subunit sigma 1) and AP1S2 (adaptor related protein complex 1 subunit sigma 2).
SGD Description
Small subunit of the clathrin-associated adaptor complex AP-1; AP-1 is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11753:SF5
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
500.60k500.65k500.70k500.75k500.80k500.85k500.90k500.95k501.00k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions