mitochondrial protein Related to Spastic paraplegia with Optic atrophy and neuropathy SPG55
Synonyms
PTH3
YLR281C
Biotype
protein coding gene
Automated Description
Enables aminoacyl-tRNA hydrolase activity. Involved in mitochondrial translation. Is active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 7 and hereditary spastic paraplegia 55. Orthologous to human MTRFR (mitochondrial translation release factor in rescue).
SGD Description
Stalled-ribosome rescue factor srRF2; mitochondrial protein required for respiratory growth in presence of bacteriostatic ribosome-binding antibiotics; not an essential gene