Gene

SMC6

Species
Saccharomyces cerevisiae
Symbol
SMC6
Name
Structural Maintenance of Chromosomes
Synonyms
  • RHC18
  • YLR383W
Biotype
protein coding gene
Automated Description
Enables damaged DNA binding activity. Contributes to SUMO transferase activity. Involved in DNA double-strand break attachment to nuclear envelope; DNA recombination; and chromosome separation. Located in nucleus and site of double-strand break. Part of Smc5-Smc6 complex. Orthologous to human SMC6 (structural maintenance of chromosomes 6).
SGD Description
Subunit of the SMC5-SMC6 complex; the SMC5-SMC6 complex plays a key role in the removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; homologous to S. pombe rad18
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19306:SF6
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
885.5k886.0k886.5k887.0k887.5k888.0k888.5k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions