Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
---|---|---|---|---|---|
Homo sapiens | ORC1 | 3 of 9 | Yes | No | ☐ ☐☐☐☑☐☐☑☑ |
Rattus norvegicus | Orc1 | 3 of 9 | Yes | No | ☐ ☐☐☐☑☐☐☑☑ |
Xenopus tropicalis | orc1 | 5 of 9 | Yes | No | ☑ ☐☑☐☐☑☑☑☐ |
Danio rerio | orc1 | 4 of 9 | Yes | No | ☐ ☐☑☐☑☐☐☑☑ |
Drosophila melanogaster | Orc1 | 4 of 9 | Yes | No | ☐ ☐☑☐☑☐☐☑☑ |
Caenorhabditis elegans | orc-1 | 3 of 9 | Yes | No | ☐ ☐☑☐☑☐☐☐☑ |
Gene symbol | Rank | Alignment Length (aa) | Similarity % | Identity % | Method Count | Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD |
---|---|---|---|---|---|---|
ORC1 | 1 | 1035 | 45 | 27 | 8 of 9 | ☑ ☑☐☑☑☑☑☑☑ |
Phenotype Term | Annotation details | References |
---|---|---|
abnormal chemical compound accumulation | ||
abnormal colony appearance | ||
abnormal liquid culture appearance | ||
abnormal meiosis | ||
abnormal protein/peptide distribution | ||
abnormal vacuolar morphology | ||
absent mating response | ||
absent pheromone sensitivity | ||
absent pheromone-induced cell cycle arrest | ||
absent respiratory growth |
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
---|---|---|---|---|---|---|---|
sir3-D205N | allele | ||||||
sir3-S67P | allele | ||||||
sir3-E137G | allele | ||||||
sir3-L738P | allele | ||||||
sir3-A136V | allele | ||||||
sir3-P179L | allele | ||||||
sir3-A2Q | allele | Yes | |||||
sir3-Δbah |
| allele | |||||
sir3-(ste8-T2E,S3E,S7E) |
| allele | |||||
sir3-1021 |
| allele |
SIR3 molecule type | Interactor gene | Interactor species | Interactor molecule type | Detection methods | Source | Reference |
---|---|---|---|---|---|---|
protein | ACO1 | Saccharomyces cerevisiae | protein |
| PMID:32051233 | |
protein | ADH6 | Saccharomyces cerevisiae | protein |
| PMID:11805837 | |
protein | APJ1 | Saccharomyces cerevisiae | protein |
| PMID:32492414 | |
protein | ARP9 | Saccharomyces cerevisiae | protein |
| PMID:25453095 | |
protein | ASF2 | Saccharomyces cerevisiae | protein |
| PMID:18794362 | |
protein | ASF2 | Saccharomyces cerevisiae | protein |
| PMID:37968396 | |
protein | BDF1 | Saccharomyces cerevisiae | protein |
| PMID:37968396 | |
RNA | CCR4 | Saccharomyces cerevisiae | protein |
| PMID:29158339 | |
protein | CHZ1 | Saccharomyces cerevisiae | protein |
| PMID:20008511 | |
protein | COR1 | Saccharomyces cerevisiae | protein |
| PMID:11805837 |
SIR3 role | SIR3 genetic perturbation | Interactor gene | Interactor species | Interactor role | Interactor genetic perturbation | Interaction type | Phenotype or trait | Source | Reference |
---|---|---|---|---|---|---|---|---|---|
unspecified role | ACS2 | Saccharomyces cerevisiae | unspecified role | synthetic growth defect (sensu BioGRID) |
| PMID:18676811 | |||
enhanced gene | ARP5 | Saccharomyces cerevisiae | enhancer gene | phenotypic enhancement (sensu BioGRID) |
| PMID:25691465 | |||
unspecified role | CDC6 | Saccharomyces cerevisiae | unspecified role | synthetic rescue (sensu BioGRID) |
| PMID:15082529 | |||
unspecified role | CDC6 | Saccharomyces cerevisiae | unspecified role | synthetic rescue (sensu BioGRID) |
| PMID:29795547 | |||
unspecified role | CDC28 | Saccharomyces cerevisiae | unspecified role | synthetic growth defect (sensu BioGRID) |
| PMID:22689984 | |||
enhancer gene | CDC73 | Saccharomyces cerevisiae | enhanced gene | phenotypic enhancement (sensu BioGRID) |
| PMID:29320491 | |||
unspecified role | CNB1 | Saccharomyces cerevisiae | unspecified role | synthetic growth defect (sensu BioGRID) |
| PMID:21712379 | |||
unspecified role | CSM3 | Saccharomyces cerevisiae | unspecified role | synthetic rescue (sensu BioGRID) |
| PMID:28389464 | |||
suppressed gene | DNL4 | Saccharomyces cerevisiae | suppressor gene | phenotypic suppression (sensu BioGRID) |
| PMID:34817085 | |||
unspecified role | DOT1 | Saccharomyces cerevisiae | unspecified role | synthetic rescue (sensu BioGRID) |
| PMID:18562671 |