Gene

PML39

Species
Saccharomyces cerevisiae
Symbol
PML39
Name
Pre-mRNA Leakage
Synonyms
  • YML107C
Biotype
protein coding gene
Automated Description
Predicted to enable zinc ion binding activity. Involved in maintenance of RNA location. Located in nuclear membrane. Part of nuclear pore nuclear basket.
SGD Description
Protein required for nuclear retention of unspliced pre-mRNAs; required along with Mlp1p and Pml1p; anchored to the nuclear pore complex through an interaction between its bimodular nuclear basket-interaction domain (NuBaID) and Mlp1p and Mlp2p; localizes to the nuclear basket enables linkage between subpopulations of Mlp1p; associates with the subset of nuclear pores farthest from the nucleolus; homologous to human ZC3HC1, a NuBaID containing protein
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
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            Sequence Feature Viewer

            Genome location
            Assembly version
            R64-5-1
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            55.3k55.4k55.5k55.6k55.7k55.8k55.9k56.0k56.1k56.2k

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            PML39 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
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              Genetic Interactions

              PML39 role
              PML39 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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