Predicted to enable helicase activity. Predicted to be involved in chromatin looping; chromatin remodeling; and chromosome organization. Located in mitochondrion. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome and primary immunodeficiency disease. Orthologous to human DHX58 (DExH-box helicase 58); RIGI (RNA sensor RIG-I); and IFIH1 (interferon induced with helicase C domain 1).
SGD Description
Putative Y' element ATP-dependent helicase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YML133C contains an intron