Enables mRNA binding activity. Involved in mRNA splicing, via spliceosome; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and response to osmotic stress. Located in nucleus. Part of commitment complex and nuclear cap binding activity complex. Orthologous to human NCBP1 (nuclear cap binding protein subunit 1).
SGD Description
Large subunit of the nuclear mRNA cap-binding protein complex; interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80