Gene

STO1

Species
Saccharomyces cerevisiae
Symbol
STO1
Name
Suppressor of TOp1
Synonyms
  • CBC1
  • CBP80
Biotype
protein coding gene
Automated Description
Enables mRNA binding activity. Involved in mRNA splicing, via spliceosome; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and response to osmotic stress. Located in nucleus. Part of commitment complex and nuclear cap binding activity complex. Orthologous to human NCBP1 (nuclear cap binding protein subunit 1).
SGD Description
Large subunit of the nuclear mRNA cap-binding protein complex; interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12412:SF2
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
518.0k518.5k519.0k519.5k520.0k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions