Version: 8.0.0
Date: Tue Jan 28 2025
ADE12
Saccharomyces cerevisiaeSGD:S000005164
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

ADE12

Species
Saccharomyces cerevisiae
Symbol
ADE12
Name
ADEnine requiring
Synonyms
  • BRA9
  • YNL220W
Biotype
protein coding gene
Automated Description
Enables DNA replication origin binding activity and adenylosuccinate synthase activity. Involved in purine nucleotide biosynthetic process. Located in cytoplasm. Orthologous to several human genes including ADSS2 (adenylosuccinate synthase 2).
SGD Description
Adenylosuccinate synthase; catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11846:SF0
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Alleles and Variants

Download all Alleles/Variants for all genes of the species

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
Data currently unavailable; sequence viewer under construction

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions