Gene

SMF1

Species
Saccharomyces cerevisiae
Symbol
SMF1
Name
Suppressor of Mitochondria import Function
Synonyms
  • SBS1
  • YOL122C
Biotype
protein coding gene
Automated Description
Enables solute:proton symporter activity. Involved in intracellular monoatomic cation homeostasis and transition metal ion transport. Located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); autoimmune disease (multiple); inflammatory bowel disease (multiple); leishmaniasis (multiple); and tuberculosis (multiple). Orthologous to human SLC11A1 (solute carrier family 11 member 1) and SLC11A2 (solute carrier family 11 member 2).
SGD Description
Divalent metal ion transporter; broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11706:SF101
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
89.8k90.0k90.2k90.4k90.6k90.8k91.0k91.2k91.4k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions