Gene

AFT2

Species
Saccharomyces cerevisiae
Symbol
AFT2
Name
Activator of Fe (iron) Transcription
Synonyms
  • YPL202C
Biotype
protein coding gene
Automated Description
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and iron-sulfur cluster binding activity. Involved in several processes, including cardiolipin metabolic process; cellular response to iron ion starvation; and regulation of phosphate transmembrane transport. Located in mitochondrion.
SGD Description
Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; AFT2 has a paralog, AFT1, that arose from the whole genome duplication
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions