Gene

YAH1

Species
Saccharomyces cerevisiae
Symbol
YAH1
Name
Yeast Adrenodoxin Homolog
Synonyms
  • YPL252C
Biotype
protein coding gene
Automated Description
Enables oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Involved in heme A biosynthetic process; iron-sulfur cluster assembly; and ubiquinone biosynthetic process. Located in mitochondrial matrix. Human ortholog(s) of this gene implicated in mitochondrial myopathy. Orthologous to human FDX2 (ferredoxin 2).
SGD Description
Ferredoxin of the mitochondrial matrix; required for formation of cellular iron-sulfur proteins; involved in heme A biosynthesis; human homolog FDX1L can complement yeast by allowing growth during down-regulation of yeast YAH1
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23426:SF34
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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73.40k73.45k73.50k73.55k73.60k73.65k73.70k73.75k73.80k73.85k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions