Enables chromatin binding activity. Involved in meiosis I cell cycle process; meiotic sister chromatid cohesion; and protein localization to chromosome, centromeric region. Located in condensed chromosome, centromeric region and condensed nuclear chromosome. Is active in chromosome, centromeric region. Orthologous to human REC8 (REC8 meiotic recombination protein).
SGD Description
Meiosis-specific component of the sister chromatid cohesion complex; alpha-kleisin family member that maintains cohesion between homologous chromosomes during meiosis I until chromosome arm-associated Rec8p is cleaved by Esp1p; cohesion between sister chromatid centromeres is maintained until metaphase of meiosis II when it is cleaved by Esp1; independent of the role in cohesion, Rec8p promotes allelic collisions and prevents nonspecific chromosome interactions; homolog of S. pombe Rec8p