Involved in several processes, including nuclear-transcribed mRNA catabolic process; positive regulation of transcription elongation by RNA polymerase II; and transcription elongation by RNA polymerase II. Located in cytoplasm. Part of CCR4-NOT core complex. Orthologous to human CNOT3 (CCR4-NOT transcription complex subunit 3).
SGD Description
Component of the CCR4-NOT core complex, involved in mRNA decapping; involved intranscription initiation and elongation and in mRNA degradation; conserved lysine in human homolog of Not5p and Not3p is mutated in cancers