Gene

NOT5

Species
Saccharomyces cerevisiae
Symbol
NOT5
Name
Negative On TATA
Synonyms
  • YPR072W
Biotype
protein coding gene
Automated Description
Involved in several processes, including nuclear-transcribed mRNA catabolic process; positive regulation of transcription elongation by RNA polymerase II; and transcription elongation by RNA polymerase II. Located in cytoplasm. Part of CCR4-NOT core complex. Orthologous to human CNOT3 (CCR4-NOT transcription complex subunit 3).
SGD Description
Component of the CCR4-NOT core complex, involved in mRNA decapping; involved intranscription initiation and elongation and in mRNA degradation; conserved lysine in human homolog of Not5p and Not3p is mutated in cancers
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23326:SF1
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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690.2k690.4k690.6k690.8k691.0k691.2k691.4k691.6k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions