Gene

CPP3

Species
Saccharomyces cerevisiae
Symbol
CPP3
Name
C-terminally Palmitoylated Protein
Synonyms
  • YDR034W-B
Biotype
protein coding gene
Automated Description
Located in plasma membrane. Is active in cell periphery and vacuolar membrane.
SGD Description
Tail-anchored plasma membrane (PM) protein; C-terminal palmitoylation is required for membrane anchoring and protein stability; PM localization is polarized to the daughter cell; also localizes to the vacuolar membrane; may be involved in response to stress; upregulated by toxic concentrations of heavy metal ions and alkali; contains a conserved cysteine rich palmitoylated domain (CYSPD, aka CYSTM); CPP3 has a paralog, MNC1, that arose from the whole genome duplication
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
MNC116060501 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
decreased metal resistance
decreased rate utilization of nitrogen source
decreased resistance to chemicals
increased innate thermotolerance
viable
Showing 1 - 5 of 5 rows
per page

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
R64-5-1
Viewer Help
521.30k521.35k521.40k521.45k521.50k521.55k521.60k521.65k521.70k521.75k
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
cpp3-Δ
  • ydr034w-b-delta
  • ydr034w-b-Δ
allele
Yes
NC_001136.10:g.521260G>Avariant
SNP
  • intergenic variant
NC_001136.10:g.521737G>Tvariant
SNP
  • intergenic variant
NC_001136.10:g.521270A>Tvariant
SNP
  • intergenic variant
NC_001136.10:g.521769T>Avariant
SNP
  • intergenic variant
NC_001136.10:g.521372A>Gvariant
SNP
  • missense variant
NC_001136.10:g.521536A>Gvariant
SNP
  • intergenic variant
NC_001136.10:g.521406T>Cvariant
SNP
  • synonymous variant
NC_001136.10:g.521481A>Gvariant
SNP
  • intergenic variant
NC_001136.10:g.521776C>Gvariant
SNP
  • intergenic variant
Showing 1 - 10 of 16 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
521.32k521.34k521.36k521.38k521.40k521.42k521.44k521.46k

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

28 interactor genes based on 28 annotations
CPP3 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
AKR1Saccharomyces cerevisiae
protein
  • protein complementation assay
PMID:18467557
RNA
NAB2Saccharomyces cerevisiae
protein
  • affinity chromatography technology
PMID:19840948
protein
SSH1Saccharomyces cerevisiae
protein
  • imaging technique
PMID:37073826
protein
TPO1Saccharomyces cerevisiae
protein
  • protein complementation assay
PMID:18467557
Showing 1 - 4 of 4 rows
per page

Genetic Interactions

CPP3 role
CPP3 genetic perturbation
Interactor gene
Interactor species
Interactor role
Interactor genetic perturbation
Interaction type
Phenotype or trait
Source
Reference
unspecified role
ATP10Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
BCS1Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
BMT2Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
COX8Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
DIT2Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
IMP2Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
LAT1Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
LIP5Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
MBA1Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
MED1Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
Showing 1 - 10 of 24 rows
per page