Gene

BOL1

Species
Saccharomyces cerevisiae
Symbol
BOL1
Name
BolA-like protein
Synonyms
  • YAL044W-A
Biotype
protein coding gene
Automated Description
Involved in [4Fe-4S] cluster assembly and protein maturation by [4Fe-4S] cluster transfer. Located in mitochondrial matrix. Orthologous to human BOLA1 (bolA family member 1).
SGD Description
Mitochondrial matrix protein involved in Fe-S cluster biogenesis; facilitates [4Fe-2S] cluster inception into mitochondrial proteins such as lipoate synthase and succinate dehydrogenase; interacts and may function with Grx5p at an early step in Fe-S cluster biosynthesis; forms dimeric complexes with Grx5p and Nfu1p that alter the stability of shared Fe/S clusters; sequence similarity to human BOLA family member, BOLA1 and S. pombe uvi31, a putative DNA repair protein
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46230:SF3
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
57.55k57.60k57.65k57.70k57.75k57.80k57.85k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions