Enables ribosome binding activity. Involved in cellular response to nutrient; cytoplasmic translational elongation; and intracellular iron ion homeostasis. Located in cytoplasm and nucleus.
SGD Description
Ribosome-associated protein; required for global translational elongation after recovery from stationary phase due to starvation; crosslinks to the 25S rRNA near the A site that overlaps the GTPase activation center, and to tRNAs; possible role in the iron deprivation response; localizes to the nucleus and cytoplasm, with enhanced nuclear localization under iron-replete conditions; null mutant exhibits slow growth during iron deprivation; orthologous to human CCDC124