Predicted to be involved in synaptic vesicle membrane organization; synaptic vesicle transport; and vacuolar transport. Predicted to be located in Golgi apparatus and axon cytoplasm. Predicted to be part of AP-3 adaptor complex. Predicted to be active in endosome membrane; presynaptic endosome; and terminal bouton. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome. Orthologous to human AP3D1 (adaptor related protein complex 3 subunit delta 1).
WB Description
apd-3 encodes an adaptin: specifically, it encodes an ortholog of the delta subunit of adaptor protein complex 3 (AP-3).