Gene

atx-2

Species
Caenorhabditis elegans
Symbol
atx-2
Name
human ATX (ataxin) related 2
Synonyms
  • CELE_D2045.1
  • D2045.1
Biotype
protein coding gene
Automated Description
Predicted to enable mRNA binding activity. Involved in several processes, including microtubule cytoskeleton organization; regulation of cell cycle process; and regulation of gene expression. Located in cytoplasm. Is expressed in body wall musculature; dorsal nerve cord; germ line; gonad; and ventral nerve cord. Used to study autosomal dominant cerebellar ataxia. Human ortholog(s) of this gene implicated in late onset Parkinson's disease and spinocerebellar ataxia type 2. Orthologous to human ATXN2 (ataxin 2) and ATXN2L (ataxin 2 like).
WB Description
atx-2 is required for early embryonic patterning; it encodes an ortholog of human ataxin-2.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12854
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
10.462M10.463M10.464M10.465M10.466M10.467M10.468M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions