Gene

cars-1

Species
Caenorhabditis elegans
Symbol
cars-1
Name
Cysteinyl Amino-acyl tRNA Synthetase 1
Synonyms
  • CELE_Y23H5A.7
  • crs-1
Biotype
protein coding gene
Automated Description
Predicted to enable ATP binding activity and cysteine-tRNA ligase activity. Predicted to be involved in cysteinyl-tRNA aminoacylation. Predicted to be active in cytoplasm. Orthologous to human CARS1 (cysteinyl-tRNA synthetase 1).
WB Description
cars-1 encodes a predicted cytoplasmic cysteinyl-tRNA synthetase (CysRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of cysteine to its cognate tRNA and is thus required for protein biosynthesis; CARS-1 is essential for embryonic and larval development, and is required for molting and a normal rate of postembryonic development.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10890
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
2.6235M2.6240M2.6245M2.6250M2.6255M2.6260M2.6265M2.6270M2.6275M2.6280M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions