Gene

cyn-16

Species
Caenorhabditis elegans
Symbol
cyn-16
Name
CYclophyliN 16
Synonyms
  • CELE_Y17G7B.9
  • cyp-16
Biotype
protein coding gene
Automated Description
Enables peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in nucleus. Predicted to be part of catalytic step 2 spliceosome. Is expressed in intestine and ventral cord neurons. Orthologous to human CWC27 (CWC27 spliceosome associated cyclophilin).
WB Description
cyn-16 encodes a highly diverged member of the cyclophilin family; CYN-16 exhibits low levels of peptidyl-prolyl cis/trans isomerase activity in vitro that is insensitive to the presence of cyclosporin A; a cyn-16::gfp fusion protein is expressed in the intestine during larval and adult stages of development, with particularly strong expression seen in the anterior and posterior ends; in dauer larvae, the cyn-16::gfp reporter is expressed in cell bodies and processes of ventral cord neurons and is no longer visible in the intestine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45625
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
12.029M12.030M12.031M12.032M12.033M12.034M12.035M12.036M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions