Gene

dgk-3

Species
Caenorhabditis elegans
Symbol
dgk-3
Name
DiacylGlycerol Kinase 3
Synonyms
  • CELE_F54G8.2
  • F54G8.2
Biotype
protein coding gene
Automated Description
Predicted to enable ATP-dependent diacylglycerol kinase activity. Involved in olfactory behavior; regulation of long-term neuronal synaptic plasticity; and thermotaxis. Predicted to be active in plasma membrane. Is expressed in head; intestine; nervous system; and pharyngeal lumen. Orthologous to human DGKA (diacylglycerol kinase alpha); DGKB (diacylglycerol kinase beta); and DGKG (diacylglycerol kinase gamma).
WB Description
dgk-3 encodes a diacylglycerol kinase that is the C. elegans ortholog of mammalian DGK-beta; dgk-3 activity is required for regulation of long-term thermotactic behavioral plasticity and for regulation of olfactory adaptation; large-scale expression studies have reported dgk-3 expression in head neurons, the intestine, and the pharyngeal lumen, while expression profiling indicates that dgk-3 is expressed in the AFD thermosensory neurons as well as a small number of additional sensory neurons.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11255
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
9.1635M9.1640M9.1645M9.1650M9.1655M9.1660M9.1665M9.1670M9.1675M9.1680M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions