Gene

div-1

Species
Caenorhabditis elegans
Symbol
div-1
Name
cell DIVision defective 1
Synonyms
  • ccd-1
  • CELE_R01H10.1
Biotype
protein coding gene
Automated Description
Predicted to enable DNA binding activity. Predicted to be involved in DNA replication initiation. Predicted to be located in nucleus. Predicted to be part of alpha DNA polymerase:primase complex. Is expressed in gonad; pharynx; vulva; and vulval precursor cell. Orthologous to human POLA2 (DNA polymerase alpha 2, accessory subunit).
WB Description
div-1 encodes a homolog of the B subunit of the DNA polymerase alpha-primase complex; DIV-1 is required in embryos for the normal timing of interphase in cell divisions, and for the asymmetric distribution of PIE-1 and P granules.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23061
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
10.2455M10.2460M10.2465M10.2470M10.2475M10.2480M10.2485M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions