Gene

eat-5

Species
Caenorhabditis elegans
Symbol
eat-5
Name
EATing: abnormal pharyngeal pumping 5
Synonyms
  • CELE_F13G3.8
  • F13G3.8
Biotype
protein coding gene
Automated Description
Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be active in gap junction and plasma membrane. Is expressed in K' cell and pharynx.
WB Description
eat-5 encodes an innexin, expressed in pharyngeal muscle cell groups pm4 and pm5, that is required for synchronized pharyngeal muscle contractions, and for normal electrical connections between pharyngeal muscle cells; EAT-5 forms electrically permeable intercellular channels (gap junctions), with a predicted membrane topology analogous to that of connexins, which affects electrical coupling between different parts of the pharynx and thus affects feeding.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11893
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
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    Transgenic Alleles

    Models

    Sequence Feature Viewer

    Genome location
    Assembly version
    WBcel235
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    7.3090M7.3095M7.3100M7.3105M7.3110M7.3115M

    Sequence Details

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    Expression

    Primary Sources
    Other Sources
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    Genetic Interactions