Predicted to enable DNA binding activity. Involved in innate immune response. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Is expressed in gonad. Orthologous to several human genes including H2BC1 (H2B clustered histone 1); H2BC10 (H2B clustered histone 10); and H2BC11 (H2B clustered histone 11).
WB Description
his-48 encodes an H2B histone; by homology, HIS-48 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-48 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.