Gene

hlh-12

Species
Caenorhabditis elegans
Symbol
hlh-12
Name
Helix Loop Helix 12
Synonyms
  • C28C12.8
  • CELE_C28C12.8
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in gonad morphogenesis; positive regulation of distal tip cell migration; and positive regulation of gene expression. Located in nucleus. Is expressed in distal tip cell and linker cell. Orthologous to human FERD3L (Fer3 like bHLH transcription factor).
WB Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in gonad morphogenesis; positive regulation of distal tip cell migration; and positive regulation of gene expression. Located in nucleus. Expressed in anterior distal tip cell; distal tip cell; linker cell; and posterior distal tip cell. Is an ortholog of human FERD3L (Fer3 like bHLH transcription factor).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23349
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
8.4786M8.4787M8.4788M8.4789M8.4790M8.4791M8.4792M8.4793M8.4794M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions