Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in several processes, including heterochromatin formation; nucleus organization; and protein localization to nuclear envelope. Predicted to be located in cytoplasm and intermediate filament. Predicted to be active in nuclear envelope and nuclear lamina. Is expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); ectodermal dysplasia (multiple); hair disease (multiple); intrinsic cardiomyopathy (multiple); and myopathy (multiple). Orthologous to several human genes including DES (desmin); GFAP (glial fibrillary acidic protein); and INA (internexin neuronal intermediate filament protein alpha).
WB Description
ifd-2 encodes a nonessential intermediate filament protein; IFD-2 is predicted to function as a structural component of the cytoskeleton; IFD-2 has no obvious function in RNAi assays.