Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to several human genes including MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1).
WB Description
JIP-1 is partly similar to the human gene ISLET-BRAIN 1 (MAPK8IP1; OMIM:604641), which when mutated leads to type II diabetes.