Gene

jip-1

Species
Caenorhabditis elegans
Symbol
jip-1
Name
JNK Interacting Protein (scaffold protein) 1
Synonyms
  • CELE_F56D12.4
  • F56D12.4
Biotype
protein coding gene
Automated Description
Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to several human genes including MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1).
WB Description
JIP-1 is partly similar to the human gene ISLET-BRAIN 1 (MAPK8IP1; OMIM:604641), which when mutated leads to type II diabetes.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11232
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
1.328M1.330M1.332M1.334M1.336M1.338M1.340M1.342M1.344M1.346M1.348M1.350M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions