Gene

kin-3

Species
Caenorhabditis elegans
Symbol
kin-3
Name
protein KINase 3
Synonyms
  • B0205.7
  • casein kinase II
Biotype
protein coding gene
Automated Description
Enables protein serine/threonine kinase activity. Involved in peptidyl-serine phosphorylation; response to hermaphrodite contact; and vulval location. Located in several cellular components, including dendrite; neuronal cell body; and non-motile cilium. Part of protein kinase CK2 complex. Is expressed in oocyte. Orthologous to several human genes including CSNK2A1 (casein kinase 2 alpha 1) and CSNK2A3 (casein kinase 2 alpha 3).
WB Description
kin-3 encodes an ortholog of the catalytic subunit of casein kinase II alpha, which in Drosophila and mammals is required for normal circadian rhythms, and which directly phosphorylates the Drosophila PERIOD protein (which itself regulates circadian rhythms); by analogy, KIN-3 might be expected to help regulate heterochronic functions dependent on such proteins as LIN-42.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24054
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
10.7345M10.7350M10.7355M10.7360M10.7365M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions