Version: 8.0.0
Date: Tue Jan 28 2025
lbp-1
Caenorhabditis elegansWB:WBGene00002253
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

lbp-1

Species
Caenorhabditis elegans
Symbol
lbp-1
Name
Lipid Binding Protein 1
Synonyms
  • CELE_F40F4.3
  • F40F4.3
Biotype
protein coding gene
Automated Description
Predicted to enable lipid binding activity. Predicted to be located in extracellular region. Is expressed in several structures, including head mesodermal cell; hypodermis; intestine; rectal gland cell; and vulval muscle.
WB Description
lbp-1 encodes a predicted secreted fatty acid binding protein (FABP) that is similar to the Ascaris suum secreted FABP As-p18; by homology, LBP-1 is predicted to function in sequestering or transporting small hydrophobic molecules such as lipids and steroid hormones; an lbp-1::gfp promoter fusion is expressed in the embryo, beginning at gastrulation, in presumptive hypodermal precursors; lbp-1::gfp hypodermal expression continues in hyp7 nuclei through hatching and is then seen only in one ventral cord neuron from the L1 to adult stages; an LBP-1::GFP fusion construct that contains the predicted LBP-1 secretory signal is secreted into the perivitelline fluid prior to hatching.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22725
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
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            Sequence Feature Viewer

            Genome location
            Assembly version
            WBcel235
            Viewer Help
            3.2592M3.2593M3.2594M3.2595M3.2596M3.2597M3.2598M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            lbp-1 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              lbp-1 role
              lbp-1 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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