Gene

mlc-3

Species
Caenorhabditis elegans
Symbol
mlc-3
Name
Myosin Light Chain 3
Synonyms
  • CELE_F09F7.2
  • F09F7.2
Biotype
protein coding gene
Automated Description
Predicted to enable calcium ion binding activity. Located in striated muscle myosin thick filament. Is expressed in body wall musculature; nervous system; non-striated muscle; and pharynx. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy 8. Orthologous to human MYL3 (myosin light chain 3) and MYL6B (myosin light chain 6B).
WB Description
mlc-3 encodes an essential myosin light chain; large-scale RNAi screens indicate that mlc-3 activity is required for both embryonic and postembryonic development, as well as for normal locomotion and egg laying.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23048
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
5.5652M5.5654M5.5656M5.5658M5.5660M5.5662M5.5664M5.5666M5.5668M5.5670M5.5672M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions