Predicted to enable calcium ion binding activity. Located in striated muscle myosin thick filament. Is expressed in body wall musculature; nervous system; non-striated muscle; and pharynx. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy 8. Orthologous to human MYL3 (myosin light chain 3) and MYL6B (myosin light chain 6B).
WB Description
mlc-3 encodes an essential myosin light chain; large-scale RNAi screens indicate that mlc-3 activity is required for both embryonic and postembryonic development, as well as for normal locomotion and egg laying.