Gene

npp-12

Species
Caenorhabditis elegans
Symbol
npp-12
Name
Nuclear Pore complex Protein 12
Synonyms
  • CELE_T23H2.1
  • T23H2.1
Biotype
protein coding gene
Automated Description
Part of nuclear pore. Orthologous to human NUP210 (nucleoporin 210) and NUP210L (nucleoporin 210 like).
WB Description
npp-12 encodes Gp210, an evolutionarily conserved membrane protein of the nuclear pore complex (NPC); NPP-12 is required for embryonic viability and normal nuclear membrane structures.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23019
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensNUP210L9 of 9YesYes   
Homo sapiensNUP2109 of 9YesYes   
Mus musculusNup210l8 of 9YesYes   
Mus musculusNup2108 of 9YesYes   
Rattus norvegicusNup2108 of 9YesYes   
Rattus norvegicusNup210l8 of 9YesYes   
Danio rerionup2108 of 9YesYes   
Drosophila melanogasterGp2109 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
WBcel235
Viewer Help
6.448M6.449M6.450M6.451M6.452M6.453M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_003279.8:g.6448893G>Avariant
SNP
  • missense variant
NC_003279.8:g.6448149C>Tvariant
SNP
  • missense variant
NC_003279.8:g.6449025G>Cvariant
SNP
  • missense variant
NC_003279.8:g.6452298C>Tvariant
SNP
  • missense variant
NC_003279.8:g.6452585C>Tvariant
SNP
  • synonymous variant
NC_003279.8:g.6453096T>Avariant
SNP
  • synonymous variant
NC_003279.8:g.6452625G>Avariant
SNP
  • missense variant
NC_003279.8:g.6449748C>Tvariant
SNP
  • missense variant
NC_003279.8:g.6452360A>Tvariant
SNP
  • missense variant
NC_003279.8:g.6447402C>Tvariant
SNP
  • missense variant
Showing 1 - 10 of 57 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
6.448M6.449M6.450M6.451M6.452M6.453MT23H2.1.1 (npp-12)T23H2.6T23H2.4.1 (mam-8)

Sequence Details

Transcript: Mode:

Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

10 interactor genes based on 10 annotations
npp-12 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
chn-1Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:36027913
protein
elks-1Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:34416233
protein
hrde-1Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:28787591
protein
igdb-2Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:28803967
protein
nrde-2Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:33055090
protein
ooc-5Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:33229589
protein
plk-1Caenorhabditis elegans
protein
  • unspecified method
PMID:37467327
protein
smo-1Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:29348603
protein
syp-2Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:32211900
protein
zen-4Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:30140741
Showing 1 - 10 of 10 rows
per page

Genetic Interactions

No data available