Version: 8.0.0
Date: Tue Jan 28 2025
pept-3
Caenorhabditis elegansWB:WBGene00003878
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

pept-3

Species
Caenorhabditis elegans
Symbol
pept-3
Name
PEPTide transporter family 3
Synonyms
  • CELE_F56F4.5
  • F56F4.5
Biotype
protein coding gene
Automated Description
Enables dipeptide transmembrane transporter activity and proton channel activity. Involved in dipeptide transport and proton transmembrane transport. Predicted to be located in membrane. Predicted to be active in apical plasma membrane. Is expressed in AVAL; AVAR; pharynx; and touch receptor neurons. Orthologous to human SLC15A1 (solute carrier family 15 member 1) and SLC15A2 (solute carrier family 15 member 2).
WB Description
pept-3 encodes a H+-coupled oligopeptide transporter; when expressed in Xenopus oocytes and mammalian cells, PEPT-3 can function in H+-coupled dipeptide transport, but in Xenopus oocytes, PEPT-3 appears to function predominantly as a H+ channel; a pept-3::gfp promoter fusion is reportedly expressed in neurons and in the pharynx.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11654
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
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    Disease
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
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      Variant
      Variant type
      Molecular consequence
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            WBcel235
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            6.1335M6.1340M6.1345M6.1350M6.1355M6.1360M6.1365M6.1370M6.1375M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            pept-3 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
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              Genetic Interactions

              pept-3 role
              pept-3 genetic perturbation
              Interactor gene
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              Interactor role
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