Gene

prx-1

Species
Caenorhabditis elegans
Symbol
prx-1
Name
PeRoXisome assembly factor 1
Synonyms
  • C11H1.4
  • C11H1.6
Biotype
protein coding gene
Automated Description
Predicted to enable ATP hydrolysis activity. Predicted to be involved in protein import into peroxisome matrix and protein unfolding. Predicted to be located in peroxisome. Predicted to be active in cytosol and peroxisomal membrane. Human ortholog(s) of this gene implicated in Heimler syndrome 1; peroxisome biogenesis disorder 1A; and peroxisome biogenesis disorder 1B. Orthologous to human PEX1 (peroxisomal biogenesis factor 1).
WB Description
prx-1 encodes a predicted peroxin, a subfamily 2 member of the AAA (ATPases Associated with diverse cellular Activities) family that affects growth in one large-scale RNAi screen; expressed in intestinal cells throughout development.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23077
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
14.314M14.316M14.318M14.320M14.322M14.324M14.326M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions