Version: 8.0.0Date: Tue Jan 28 2025
Gene
prx-12
- Species
- Caenorhabditis elegans
- Symbol
- prx-12
- Name
- PeRoXisome assembly factor 12
- Synonyms
- CELE_F08B12.2
- F08B12.2
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable ubiquitin-protein transferase activity. Involved in nematode larval development and peroxisome organization. Predicted to be located in membrane and peroxisome. Predicted to be part of peroxisomal importomer complex. Predicted to be active in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 3A and peroxisome biogenesis disorder 3B. Orthologous to human PEX12 (peroxisomal biogenesis factor 12).
- WB Description
- Predicted to enable ubiquitin-protein transferase activity. Involved in nematode larval development and peroxisome organization. Predicted to be located in peroxisomal membrane. Predicted to be part of peroxisomal importomer complex. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 3A and peroxisome biogenesis disorder 3B. Is an ortholog of human PEX12 (peroxisomal biogenesis factor 12).
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR12888
Stringency:
Additional filters to further constrain the results:
| Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
|---|---|---|---|---|---|
| Homo sapiens | PEX12 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Mus musculus | Pex12 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Rattus norvegicus | Pex12 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Xenopus tropicalis | pex12 | 5 of 9 | Yes | Yes | ☑ ☐☐☑☑☐☑☑☐ |
| Danio rerio | pex12 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Drosophila melanogaster | Pex12 | 8 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☐☑ |
| Saccharomyces cerevisiae | PEX12 | 8 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☐ |
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Phenotypes
- Primary Sources
- Other Sources
- None
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Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Species | Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
|---|---|---|---|---|---|---|---|---|
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Alleles and Variants
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
|---|---|---|---|---|---|---|---|
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Transgenic Alleles
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
|---|---|---|---|---|---|---|---|
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Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
|---|---|---|---|---|---|
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Sequence Feature Viewer
- Genome location
- ChrX:11393294...11394619 + (1.33 kb)
- Assembly version
- WBcel235
- Viewer Help
Data currently unavailable; sequence viewer under construction
Expression
- Primary Sources
- Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.