Gene

smg-4

Species
Caenorhabditis elegans
Symbol
smg-4
Name
Suppressor with Morphological effect on Genitalia 4
Synonyms
  • CELE_F46B6.3
  • F46B6.3
Biotype
protein coding gene
Automated Description
Predicted to enable mRNA binding activity. Involved in male genitalia development and nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Located in nucleus and perinuclear region of cytoplasm. Is expressed in intestinal cell; muscle cell; and neurons. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 14. Orthologous to human UPF3A (UPF3A regulator of nonsense mediated mRNA decay) and UPF3B (UPF3B regulator of nonsense mediated mRNA decay).
WB Description
Predicted to enable mRNA binding activity. Involved in male genitalia development and nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Located in nucleus and perinuclear region of cytoplasm. Expressed in intestinal cell; muscle cell; and neurons. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 14. Is an ortholog of human UPF3A (UPF3A regulator of nonsense mediated mRNA decay) and UPF3B (UPF3B regulator of nonsense mediated mRNA decay).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13112
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
9.7760M9.7762M9.7764M9.7766M9.7768M9.7770M9.7772M9.7774M9.7776M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions