Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process and sphingomyelin biosynthetic process. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane; endoplasmic reticulum membrane; and plasma membrane. Is expressed in several structures, including body wall musculature; pharyngeal cell; rectal muscle; ventral nerve cord; and vulval muscle. Human ortholog(s) of this gene implicated in calvarial doughnut lesions with bone fragility. Orthologous to several human genes including SGMS2 (sphingomyelin synthase 2).
WB Description
Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process and sphingomyelin biosynthetic process. Predicted to be located in Golgi membrane; endoplasmic reticulum membrane; and plasma membrane. Expressed in head muscle; pharyngeal cell; rectal muscle; spermatheca; and vulval muscle. Human ortholog(s) of this gene implicated in calvarial doughnut lesions with bone fragility. Is an ortholog of human SGMS2 (sphingomyelin synthase 2).