Version: 8.0.0Date: Tue Jan 28 2025
Gene
snr-5
- Species
- Caenorhabditis elegans
- Symbol
- snr-5
- Name
- Small Nuclear Ribonucleoprotein 5
- Synonyms
- CELE_ZK652.1
- ZK652.1
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytosol and nucleus. Predicted to be part of U1 snRNP; catalytic step 2 spliceosome; and pICln-Sm protein complex. Is expressed in several structures, including enteric muscle; excretory cell; hypodermis; nervous system; and reproductive system. Orthologous to human SNRPF (small nuclear ribonucleoprotein polypeptide F).
- WB Description
- snr-5 encodes an ortholog of human small nuclear ribonucleoprotein SmF, a protein that forms part of a heptameric complex required for biogenesis and function of the snRNPs that catalyze mRNA splicing; in combination with the gene that encodes the human SmE and SmG orthologs (snr-6 and snr-7, respectively), snr-5 affects embryonic viability and nuclear association and localization of P granules in embryos, based on an RNAi assay; affects embryonic and larval viability based on large-scale RNAi assays; snr-5 is expressed in embryos and adult gonads.
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR11021
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Phenotypes
- Primary Sources
- Other Sources
- None
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Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
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Alleles and Variants
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
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Transgenic Alleles
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
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Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
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Sequence Feature Viewer
- Genome location
- ChrIII:7862070...7862574 + (0.50 kb)
- Assembly version
- WBcel235
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Expression
- Primary Sources
- Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.