Gene

snr-7

Species
Caenorhabditis elegans
Symbol
snr-7
Name
Small Nuclear Ribonucleoprotein 7
Synonyms
  • 1D295
  • CELE_Y71F9B.4
Biotype
protein coding gene
Automated Description
Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in P granule. Is expressed in gonad. Orthologous to several human genes including SNRPG (small nuclear ribonucleoprotein polypeptide G).
WB Description
snr-7 encodes the C. elegans ortholog of the small nuclear ribonucleoprotein G, one of seven subunits of the heptameric Sm complex required for the biogenesis and function of snRNPs that catalyze mRNA splicing; in addition to its predicted role in pre-mRNA processing, SNR-7 activity is essential for embryogenesis and for several aspects of germ cell specification including localization and subcellular distribution of P granules and maintenance of transcriptional quiescence; snr-7 is also required for RNA interference and for the overall health and fertility of the animal; immunostaining of adults and embryos using antibodies raised against mammalian Sm proteins and mammalian SmG, in particular, suggests that SNR-7 localizes to the nucleus and cytoplasm in many cell types, as well as to P granules in germ cells and their embryonic precursors.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10553
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
2.72705M2.72710M2.72715M2.72720M2.72725M2.72730M2.72735M2.72740M2.72745M2.72750M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions