Gene

syx-5

Species
Caenorhabditis elegans
Symbol
syx-5
Name
SYntaXin 5
Synonyms
  • CELE_F55A11.2
  • F55A11.2
Biotype
protein coding gene
Automated Description
Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in several processes, including endoplasmic reticulum to Golgi vesicle-mediated transport; synaptic vesicle docking; and vesicle fusion. Predicted to be located in membrane and presynapse. Predicted to be part of SNARE complex. Predicted to be active in Golgi membrane. Is expressed in several structures, including anal depressor muscle; excretory gland cell; nervous system; pharynx; and reproductive system. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Orthologous to human STX5 (syntaxin 5).
WB Description
syx-5 is an ortholog of human STX5 (syntaxin 5); syx-5 is involved in apoptotic process, embryo development, hermaphrodite genitalia development, locomotion, nematode larval development, positive regulation of growth, receptor-mediated endocytosis, reproduction and secretion by cell; syx-5 is expressed in the pharynx, anal depressor muscle, nervous system, reproductive system, excretory gland cell, and the body wall musculature; at the sub-cellular level, SYX-5::GFP shows a punctate pattern in the epidermis that could correspond to the Golgi apparatus, in addition to a faint pattern highly reminiscent of adherens junctions.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19957
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
11.7650M11.7652M11.7654M11.7656M11.7658M11.7660M11.7662M11.7664M11.7666M11.7668M11.7670M11.7672M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions