Enables actin filament binding activity and gap junction channel activity. Involved in monoatomic ion transmembrane transport and positive regulation of locomotion. Located in gap junction. Is expressed in several structures, including anchor cell; muscle cell; neurons; phasmid sheath cell; and somatic nervous system.
WB Description
unc-9 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; UNC-9 is required for normal forward locomotion and egg-laying and also plays a role in the response to antihelminthics and volatile anesthetics; UNC-9 may form a functional pair with UNC-7, another C. elegans innexin, as mutations in unc-7 result in defects nearly identical to those in unc-9 mutant animals.