Gene

C38H2.2

Species
Caenorhabditis elegans
Symbol
C38H2.2
Name
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Synonyms
  • CELE_C38H2.2
Biotype
protein coding gene
Automated Description
Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Is expressed in several structures, including intestine; nervous system; pharynx; rectal gland cell; and reproductive system. Orthologous to human C1GALT1 (core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1).
WB Description
C38H2.2 encodes a core 1 UDP-Gal:GalNAcalpha1-Ser/Thrbeta1,3-galactosyltransferase (core 1 beta3-Gal-T or T-synthase,EC2.4.1.122); C38H2.2 protein is predicted to be primarilyextracellular, with an N-terminal transmembrane domain; C38H2.2 shares 6conserved cysteine residues with all known T-synthases, and isubiquitously expressed; enzymatically active C38H2.2 can be generatedfrom insect but not mammalian cells, suggesting thatinvertebrate-specific chaperones are required for its activity.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23033
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
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10.3820M10.3825M10.3830M10.3835M10.3840M10.3845M10.3850M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions