Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Is expressed in several structures, including intestine; nervous system; pharynx; rectal gland cell; and reproductive system. Orthologous to human C1GALT1 (core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1).
WB Description
C38H2.2 encodes a core 1 UDP-Gal:GalNAcalpha1-Ser/Thrbeta1,3-galactosyltransferase (core 1 beta3-Gal-T or T-synthase,EC2.4.1.122); C38H2.2 protein is predicted to be primarilyextracellular, with an N-terminal transmembrane domain; C38H2.2 shares 6conserved cysteine residues with all known T-synthases, and isubiquitously expressed; enzymatically active C38H2.2 can be generatedfrom insect but not mammalian cells, suggesting thatinvertebrate-specific chaperones are required for its activity.