Gene

F10C2.4

Species
Caenorhabditis elegans
Symbol
F10C2.4
Name
DNA polymerase delta catalytic subunit
Synonyms
  • CELE_F10C2.4
Biotype
protein coding gene
Automated Description
Predicted to enable 3'-5'-DNA exonuclease activity and DNA-directed DNA polymerase activity. Predicted to be involved in DNA replication proofreading; base-excision repair, gap-filling; and nucleotide-excision repair, DNA gap filling. Predicted to be located in nucleus. Predicted to be part of delta DNA polymerase complex. Orthologous to human POLD1 (DNA polymerase delta 1, catalytic subunit).
WB Description
F10C2.4 encodes a homolog of the DNA polymerase delta complex subunit A that is required in embryos for the normal timing of embryonic cell divisions (much as DIV-1 is) and, also, for normal chromosome segregation (probably because of defective DNA replication).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10322
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
12.0420M12.0425M12.0430M12.0435M12.0440M12.0445M12.0450M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions